Merits of Flow Production As the business size increases in size, there is a need to increase the method of production to enable a greater production in capacity. A small business can use job or batch production to give a personalized or unique product but if the product is targeted for a larger, mass markets then there might be a needed to be produced efficiently, and a key method in these situations is flow production. Flow production incorporates the continuous movement of items through the manufacturing process, and this means that that when one task is finished the other task can start immediately thus the time taken on a task remains constant. Flow production, also termed as mass production involves the use of production lines like in a carmaker where bonnets, engines, doors, and wheels are added to a chassis as it moves down the assembly line. Flow chemistry has many advantages such as the fact that it is safer for reactions when handling dangerous chemicals thus the high surface area to volume ratio of flow reactors increases the efficacy of heat removal thus ensuring that the highly exothermic reaction can be controlled safely. Continuous flow chemistry allows small levels of dangerous intermediate to be created at any instant and to create the desired and less hazardous product and the standard of hazardous material processed at any time is minimized in flow compared to when it is produced with batch. The reactions that emit gas are much safer if the flow is at a maximum rate of gas production is limited by the speed at which the reagents are pumped, and in batch reactors where all the reactants are present at the same time then the gas evolution rate can be hard to control in an explosion.
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It is worth noting that flow reactors have no need for headspace and the pressure within the reactor is controlled by a device called a back pressure regulator (BPR) and by not pressuring the gas in the head space like the traditional batch reactors and this eliminates the hazard that is associated with a volume of high pressure compressed vapor or gas.
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Reaction times in continuous flow production can be precisely controlled down to some seconds or less thus allowing the rapid creation of reactive intermediates to be reacted immediately in the other reaction step, and multi-step telescope reactions provide a route to complex organic transformations avoiding the steps of isolating intermediates. A fact worth stating is that flow reactors can be easily pressured and safely pressured using Vapourtec’s R-series reactor pressure of 200 bars, and this enables the reaction temperatures to be above the normal boiling point of the solvent (like the liquid phase reactions with ethanol at 250C) that provide reaction rates that are 1000s time faster than under reflux conditions.